Cross-Tivity : Role of early life CROSS-feeding alterations on visceral sensiTIVITY 

The Cross-Tivity project aims to study how alterations in early gut colonization and metabolic interactions between the initial microorganisms (cross-feeding) disrupt microbiota development, as well as the host's immune and metabolic maturation, notably promoting the visceral hyperalgesia observed in infants with colic. By combining in silico, in vitro, and in vivo approaches, the project aims to identify the involved microbiota–host mechanisms in order to develop new strategies to prevent the long-term health consequences of early dysbiosis.