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DImaCell facility

We support researchers and entrepreneurs using spectroscopy and multi-scale photonic imaging.

DImaCell (Cell Imaging Facility) is the Bourgogne Franche-Comté regional platform for cellular imaging. It has IBISA accreditation since 2015.

Founded in 2009, it offers high-level technologies and methodologies in cellular imaging, for applications in a wide range of research fields: medical, agronomy, agri-food, etc. Equipments are accessible to the entire scientific community (universities, EPST) and also private companies.

The platform is spread over two sites: on the Dijon campus and one site on the Besançon campus. The Spectroscopic Imaging Platform (PIMS) is part of the UMR PAM. It is one of the two Dijon sites.

The spectroscopic imaging site (PIMS)

Description

The technical platform PIMS (Spectroscopic imagery plateform) offers imagery and analysis techniques dedicated to the observation of environmental perturbations applied to the micro-organisms of interest, such as pressure, temperature or oxidation
The samples observed range from micro-organisms (yeasts, bacteria, filamentous fungi) to macromolecules and bio-polymers (food matrices, emulsions, functionalised packaging films).

 

Our activities

  • provision of photonic imaging and spectroscopy equipments, with technical support,
  • advice and/or training for users,
  • collaborative research,
  • training for PhD and Masters students and organisation of group training courses.

Available techniques

Photonic imaging:
  • Wide-field microscopes (fluorescence and bright field)
  • Multiphoton microscope
  • FLIM module (time resolved microscopy)
  • PALM / STORM super-resolved microscopy
  • OPTIR infrared and Raman microspectroscopy

Spectrometry:
  • Fluorescence spectrometry in cuvette
  • Plate reader (fluorescence and absorption)
  • Fluorescence lifetime measurements
  • Anisotropy measurements

A sample preparation area is available to users (PSM, centrifuge, incubator, etc…).